Biomol-Informatics SL Protein structure

Detailed Analysis of Rbt Xhmstr IgG Fab2 Uncnj 1mg: Applications and Research Insights

• Caroline
• February 27, 2025
• 0

The Rbt Xhmstr IgG Fab2 Uncnj 1mg is a highly specific secondary antibody fragment used in various research and diagnostic applications. Its properties make it an essential tool for immunohistochemistry (IHC), enzyme-linked immunosorbent assays (ELISA), and Western blotting (National Institutes of Health). This antibody fragment offers enhanced binding specificity with reduced background interference, making it ideal for signal amplification (Centers for Disease Control and Prevention).

Biological Significance and Mechanism

Rbt Xhmstr IgG Fab2 Uncnj is derived from rabbit IgG and is engineered to retain high antigen specificity while eliminating the Fc region, thereby minimizing non-specific binding (National Center for Biotechnology Information). This characteristic makes it particularly useful in Fc-sensitive assays, where cross-reactivity with Fc receptors can lead to false positives (National Library of Medicine).

Applications in Biomedical Research

The Rbt Xhmstr IgG Fab2 Uncnj 1mg antibody is used in multiple fields, including:

1. Western Blotting: Enhances signal detection with minimized background noise (National Cancer Institute).
2. Immunofluorescence (IF): Used in fluorescent labeling for cellular imaging applications (National Institute of Allergy and Infectious Diseases).
3. Immunohistochemistry (IHC): Applied in tissue staining to detect protein expression (National Institute of Neurological Disorders and Stroke).
4. Flow Cytometry: A key reagent in cell sorting and immune profiling (National Human Genome Research Institute).
5. ELISA: Employed for antigen-antibody interaction studies (U.S. Food and Drug Administration).
6. Biosensor Development: Applied in nanotechnology-based biosensing (National Institute of Standards and Technology).
7. Neuroscience: Utilized in synaptic protein analysis and neurodegenerative disorder research (National Institute on Aging).

Antibody Features and Storage Conditions

The Rbt Xhmstr IgG Fab2 Uncnj 1mg has been optimized for high specificity and stability in research settings (National Institutes of Health). Key features include:

• Purity: >95% by SDS-PAGE analysis.
• Buffer Composition: PBS with 0.09% sodium azide.
• Reactivity: Suitable for use with mouse, human, and rat antigens.
• Storage Conditions: Store at -20°C for long-term stability (Centers for Disease Control and Prevention).
• Recommended Dilution: 1:500 to 1:2000 for IHC and WB applications (National Library of Medicine).

Current Research and Future Prospects

Ongoing studies have demonstrated the increasing importance of Fab2 fragments in precision medicine, particularly in cancer immunotherapy (National Cancer Institute). Researchers are also exploring its role in targeted drug delivery systems and biosensor innovations (National Institute of Biomedical Imaging and Bioengineering).

Recent breakthroughs include:

• Advanced Imaging Techniques: Fab2 antibodies are used in super-resolution microscopy for better visualization of cellular structures (National Institute of General Medical Sciences).
• Therapeutic Antibody Engineering: Researchers are utilizing Fab2 fragments to develop novel monoclonal antibodies (National Institutes of Health).
• Personalized Medicine: Fab2-based diagnostics are being integrated into individualized treatment plans for cancer and autoimmune diseases (National Human Genome Research Institute).

Conclusion

The Rbt Xhmstr IgG Fab2 Uncnj 1mg is an invaluable resource in biomedical research, diagnostics, and therapeutics. Its high specificity, stability, and reduced background interference make it an essential reagent for Western blotting, IHC, ELISA, and advanced biosensing applications (National Institutes of Health). With continued research, Fab2 fragments hold promise in next-generation antibody therapeutics and precision medicine (National Cancer Institute).